Research Assistant (m/f/d) RNA processing in stress-related neural memory

The Institute of Molecular Biology gGmbH (IMB) is a Centre of Excellence for Life Sciences, funded by the Boehringer Ingelheim Foundation. It is located within the campus of the Johannes Gutenberg-University, Mainz, Germany.

Get research experience with the possibility to prestart a PhD Position

Understanding how we learn and store memory is of fundamental interest for basic research, but also carries important translational significance in the context of brain dysregulations, such as mental retardation, cognitive decline with age, and post-traumatic stress disorder. The formation of a neural memory includes the crucial phase of memory consolidation, which requires behaviorally induced alterations in the availability of functional mRNAs.  In this project, you will investigate how the stress protein Gadd45a regulates stress-related memory formation by specifically stabilizing extended 3’UTRs (3´ untranslated regions; Aparisi Rey et al EMBO Rep. (2019)).  You will apply RNA-seq and Omics approaches and analyze the role of 3’UTRs in synaptic mRNA localization in neuronal cultures, employing confocal microscopy.   

See also  www.imb-mainz.de/research-at-imb/niehrs/research/  

 You have

  • Master´s degree in a relevant biomedical area
  • Preferably experience in neurobiology
  • Good communication skills and good team spirit
  • Ability to solve problems independently
  • Fluent in English (spoken and written)

We offer

  • An international and vibrant working environment
  • Competitive stipend
  • Training opportunities

To apply please send a SINGLE PDF file containing your cover letter stating research and career interests, CV, scans of your degrees (Germans: including copies of Abitur- & Master degree), and contact details of 2 references to hr@imb-mainz.de, stating job reference CNRA01. Initial employment will be as Research Assistant with the opportunity to apply for and transfer to the International PhD Programme (IPP) https://www.imb.de/students-postdocs/international-phd-programme.  

Start date:         By September 1st, 2021

Deadline:           May 15th, 2021

Duration:           Up to 9 months with the option of transferring to a PhD position

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